Treatment and Prevention

How to use the drug Irbesartan?

Irbesartan is a drug used to treat hypertension. It is made in the form of tablets. Before use, you should consult with your doctor; self-medication can be dangerous for the life and health of the patient.

International non-proprietary name

The drug is called Irbesartan (INN).

Irbesartan is a drug used to treat hypertension.

ATH

Drug Code - C09CA04.

Forms of release and composition

The drug is available in the form of white biconvex tablets. The shape is round. From above are covered with a film cover.

The active ingredient is hydrochloride irbesartan, which in 1 pc. contains 75 mg, 150 mg or 300 mg. Auxiliary substances - microcrystalline cellulose, magnesium stearate, colloidal silicon dioxide, povidone K25, lactose monohydrate, croscarmellose sodium.

The drug Irbesartan is an antihypertensive agent.
The drug is available in the form of white biconvex tablets. The shape is round.
The active ingredient of the drug is irbesartan hydrochloride, which in 1 pc. contains 75 mg, 150 mg or 300 mg.

pharmachologic effect

The drug interferes with the action of the hormone angiotensin 2 on the receptors in the cardiovascular system and kidneys. The drug is a hypotensive agent. Makes lower pressure in the pulmonary circulation, reduces overall peripheral resistance. Slows the development of renal failure.

Pharmacokinetics

Rapidly absorbed by 60-80%. After 2 hours, the maximum concentration in the blood. A large number of substances associated with proteins. Metabolized in the liver, displayed on 80% of this body. Partially excreted by the kidneys. Removal of the drug takes 15 hours.

Indications for use

The drug is prescribed for antihypertensive therapy. Used for hypertension and diabetic nephropathy.

Contraindications

The drug is not prescribed to children under 18 years old, since the efficacy and safety of the drug at this age have not been studied. It is not used in case of hypersensitivity to the components, while carrying a child and while breastfeeding. Relative contraindications are also aortic or mitral valve stenosis, renal artery stenosis, diarrhea, vomiting, hyponatremia, dehydration, chronic heart failure.

The drug is not prescribed to children under 18 years old, since the efficacy and safety of the drug at this age have not been studied.
The drug is not used during childbirth.
Renal artery stenosis is a contraindication to receive Irbesartan.
A relative contraindication is chronic heart failure.
Diarrhea is a contraindication to receive the drug.
The drug should not be taken with vomiting.
The drug can cause sexual dysfunction.

How to take Irbesartan?

Tablets are taken orally before meals or during meals. Treatment begins with 150 mg per day. Later, the dosage is increased to 300 mg per day. Since a further increase in the dose leads to an increase in the effect, it is prescribed simultaneous use with diuretics. Older people suffering from dehydration and on hemodialysis are prescribed the first dosage of 75 mg per day, since arterial hypotension may occur.

In case of kidney failure, it is necessary to control the level of creatinine in the blood, to avoid hyperkalemia.

In cardiomyopathy, caution should be exercised, since the likelihood of myocardial infarction is high.

With diabetes

In case of diabetes mellitus type 2, the medicine is used in combination therapy.

Side effects of Irbesartan

Some patients have negative reactions to the drug. Hepatitis, hyperkalemia may occur. Sometimes the functioning of the kidneys is disturbed, in men - sexual dysfunction. The temperature of the skin may increase.

Gastrointestinal tract

Nausea, vomiting are possible. Sometimes there is a distorted perception of taste, diarrhea, heartburn.

central nervous system

A person gets tired faster, may have dizziness. Headaches are less common.

On the part of the respiratory system

Chest pain, cough may appear.

Since the cardiovascular system

Perhaps the appearance of heart disease, tachycardia.

After application of the drug may cause convulsions.
On the part of the musculoskeletal system, pain in the muscles.
Some patients note the occurrence of allergic reactions: itching, rash, urticaria.
On the part of the respiratory system may appear cough.
After taking the medicine, heartburn is sometimes observed.
When using the medication a person may have dizziness.

From the musculoskeletal system

There are pains in muscles, myalgia, arthralgia, cramps.

Allergies

Some patients note the occurrence of allergic reactions: itching, rash, urticaria.

Influence on ability to operate mechanisms

Due to dizziness, it is recommended to refrain from driving during the course of therapy.

special instructions

Some groups of patients should take the drug with caution.

Use in old age

Patients older than 75 years are prescribed lower dosages to avoid possible complications.

Purpose of Irbesartan to children

Till 18 years the medicine is not prescribed.

With an overdose of Irbesartan, a decrease in blood pressure is observed.
In case of overdose, the victim should wash the stomach.
Patients with diabetes are contraindicated for the simultaneous use of the drug with aliskiren-containing drugs.
Patients older than 75 years are prescribed lower dosages to avoid possible complications.
Breastfeeding mothers drug is prohibited.

Use during pregnancy and lactation

Pregnant women and lactating mothers are prohibited.

Irbesartan Overdose

In case of overdose, tachycardia or bradycardia, collapse, decrease in blood pressure are noted. The victim should take activated charcoal, flush the stomach, and then proceed to symptomatic treatment.

Interaction with other drugs

It is necessary to inform the doctor about all the drugs used: some combinations may be dangerous to life and health. In some situations, concurrent administration with hydrochlorothiazide is indicated.

Contraindications

Prohibited combination with ACE inhibitors in diabetic nephropathy. Patients with diabetes are contraindicated for simultaneous use with aliskiren containing drugs. The remaining patients such combinations require caution.

Combinations not recommended

It is not recommended to combine with drugs containing potassium. May increase the amount of trace element in the blood.

Combinations that require caution

It is not recommended to combine with taking lithium preparations. With caution taken simultaneously with diuretics and other antihypertensive drugs to avoid renal dysfunction.

Compatibility with alcohol

It is not recommended to combine treatment with the use of alcoholic beverages, since the risk of side effects and complications increases.

It is not recommended to combine treatment with the use of alcoholic beverages, since the risk of side effects and complications increases.
The agent Azilsartan may be used, the active ingredient in which is Azilsartan medoxomil.
An effective analogue of the drug is Aprovel.
Doctors prescribe the use of Irbesartan Canon for some patients.
Losartan is a similar drug.

Analogs

The drug has analogues, synonyms. Effective is considered Aprovel. On the basis of medoxomil olmesartan produce Cardosal. Other analogues are Telmisartan, Losartan. The agent Azilsartan may be used, the active ingredient in which is Azilsartan medoxomil. Doctors prescribe the use of Irbesartan Canon for some patients.

Pharmacy vacation terms

You can buy medicine by prescription only.

Price for Irbesartan

In Russia, the drug can be purchased for 400-575 rubles. The cost varies depending on the pharmacy, the region.

Drug storage conditions

Store in original packaging at a temperature of + 25 ... + 30 ° C in a dry and dark place out of the reach of children.

Shelf life

The drug is valid for 2 years from the production date, after which it should be disposed of.

Manufacturer

The drug produces Kern Pharma S.L., Spain.

Quickly about medications. Losartan

Reviews of Irbesartan

Tatiana, 57, Magadan: “The doctor prescribed medicine for the treatment of diabetic nephropathy. I took it at the prescribed dosage according to the prescribed regimen. I began to feel better. Of the minuses of treatment, I can call the high cost of the medicine and dizziness that occurred after taking it.”

Dmitry, 72, Vladivostok: “In his youth, he suffered from high blood pressure, his condition began to deteriorate with age: tinnitus appeared, headaches in the back of his head. At first he endured, but then he went to the doctor. The doctor prescribed Irbesartan treatment. He took the drug month. The condition stabilized, but then pressure began to jump again. The doctor said to apply regularly. Again he began to feel better. It is also good that the price, although not small, but not excessively high. "

Ludmila, 75 years old, Nizhny Novgorod: “Because of pressure surges, I had to turn to a general practitioner. The doctor picked up a medicine. Every day I take 1 tablet for prophylaxis, helps well. The pressure returned to normal, and the dependence on weather conditions disappeared. A good remedy and effective, recommend".

Watch the video: High Blood Pressure: What You Need to Know About Medications (November 2019).

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