Treatment and Prevention

How to use the drug Amoxil 500?

Amoxil 500 is a drug that belongs to the group of drugs with antimicrobial action. This semisynthetic antibiotic has a wide spectrum of action, due to which it is widely used in medicine.

International non-proprietary name

The name Amoxicillin was adopted as the generic international name.

Amoxil 500 is a drug that belongs to the group of drugs with antimicrobial action.


ATH code - J01CA04.

Forms of release and composition

Amoxil with a dosage of 500 mg is produced in the form of tablets having a white color or a slightly yellow tint. Tablets are placed in blisters of 10 pcs. Packaging of the medicine is a cardboard box in which there are 2 blisters.

The active ingredient of this medication is amoxicillin. Its amount in each tablet is 500 mg.

Additional elements are:

  • calcium stearate;
  • potato starch;
  • Povidone.

Amoxil with a dosage of 500 mg is produced in the form of tablets.

pharmachologic effect

This aminopenicillin antibiotic is characterized by a broad spectrum of action. When interacting with bacteria, it inhibits the cells, resulting in a bactericidal effect. The drug shows high efficacy against the following microorganisms:

  • staphylococcus;
  • enterococci;
  • Corynebacterium diphtheria;
  • streptococci;
  • hemophilic and E. coli;
  • protea;
  • neisserii meningitis and gonorrhea;
  • shigella;
  • salmonella;
  • peptokokki;
  • peptostreptokokki;
  • clostridia.
The drug shows high efficacy against streptococcus.
The drug shows high efficacy against enterococcus.
The drug shows high efficacy against Corynebacterium diphtheria.
The drug shows high efficacy against staphylococcus.
The drug shows high efficacy against Escherichia coli.
The drug shows high efficacy against neisseriya meningitis and gonorrhea.
The drug shows high efficacy against shigella.

When administered with metronidazole, it is able to eliminate Helicobacter pylori.

Immune to medication microorganisms:

  • mushrooms;
  • mycoplasma;
  • protea;
  • Pseudomonas aeruginosa;
  • rickettsia;
  • amoeba;
  • plasmodia;
  • viruses.


The absorption of the drug begins in the small intestine. Food has almost no effect on the speed and percentage of absorption - on average, the substance is absorbed by 85-90%. The maximum concentration of amoxicillin in the blood plasma is achieved 1-2 hours after taking the pill. The drug quickly penetrates into many tissues of the body: bone, mucous membranes, sputum, intraocular fluid. About 20% of the active substance reacts with plasma proteins.

Amoxicillin metabolism occurs partially, since most of its metabolites are not active.

The half-life of the antibiotic reaches 1-1.5 hours. After 6 hours, the drug is excreted through the kidneys.

Indications for use

Amoxyl is prescribed for:

  • bacterial lesions of the urinary tract and kidneys (cervicitis, cystitis, pyelonephritis, urethritis, gonorrhea);
  • inflammatory diseases of soft tissues and skin (impetigo, wound infections, erysipelas);
  • respiratory infections (otitis, sinusitis, pneumonia, bronchitis, tonsillitis);
  • diseases of the gastrointestinal tract of bacterial origin (among them enterocolitis, typhoid fever and inflammatory processes in the bile ducts).
Amoxil is prescribed in the face.
Amoxil prescribed for cystitis.
Amoxil is prescribed for pneumonia.
Amoxil is prescribed for urethritis.
Amoxil is prescribed for typhoid fever.
Amoxil is prescribed for otitis.
Amoxil is prescribed for gonorrhea.


Before taking the drug should be familiar with the list of contraindications in the instructions for use:

  1. The presence of hypersensitivity to the components of the tablets.
  2. Sensitization to penicillins.
  3. The presence of reactions to the reception of beta-lactam agents.
  4. Leukemoid reactions of the lymphatic type or mononucleosis is infectious.
  5. Age up to 1 year (infants).


With extreme caution, Amoxyl is prescribed to patients with the following diagnoses:

  • allergic diathesis;
  • history of asthma;
  • viral infections;
  • acute lymphatic leukemia.
With extreme caution Amoxyl prescribed to patients with asthma in history.
With extreme caution Amoxyl prescribed to patients with allergic diathesis.
With extreme caution, Amoxyl is prescribed to patients with lymphatic leukemia.

Amoxicillin in such pathologies should be taken only in extreme cases. In this case, the dosage and duration of administration is calculated individually.

How to take Amoxil 500?

Tablets are taken orally with water. Chew or crush the tablet should not be. Medication may occur before or after a meal. The volume of a single dose depends on the age of the patient and the severity of the disease. Often used the following treatment regimen.

Adult patients and children over 10 years old with mild to moderate severity of the disease are prescribed 250-500 mg of the drug three times a day. Treatment of pneumonia, sinusitis and other serious diseases requires an increase in a single dosage to 500-1000 mg of the drug 3 times a day. The maximum daily volume of the drug is 6 mg.

For children whose body weight is less than 40 kg, the daily dose is calculated using the formula: 40-90 mg / kg. The resulting volume is divided into 3 doses. The maximum daily dose - 3 g.

If the disease occurs in mild or moderate severity, then the duration of the course reaches 5-7 days. Infections that are caused by staphylococcus require longer treatment (minimum 10 days).

In chronic infections and illnesses in a severe degree, doctors choose an individual dose and duration. It largely depends on the diagnosis, the type of pathogen, the general condition of the patient.

Treatment should be completed 40 hours after the removal of symptoms of the disease.

With diabetes

In patients with a diagnosis of diabetes, infectious diseases occur frequently. In the framework of complex therapy, doctors prescribe amoxicillin-based antibiotics. At the same time, you should carefully follow the recommendations of a specialist and follow the dosage. Hypoglycemic drugs can affect the activity of antibacterial agents.

Doctors prescribe amoxicillin-based antibiotics to patients with diabetes mellitus.

Side effects

Patients taking this antibiotic may experience some unwanted effects.

Gastrointestinal tract

On the part of this system, disorders of the digestive tract often occur:

  • decreased appetite;
  • upset stool (diarrhea);
  • violation of taste sensations;
  • dry mouth;
  • nausea, often resulting in vomiting;
  • discomfort in the abdomen, pain, bloating;
  • the appearance of a dark shade on the tongue;
  • itching anus;
  • antibiotic-associated colitis.

All the listed symptoms are reversible (eliminated after discontinuation of the drug).


In some cases, there are low rates of platelets, basophils, leukocytes and neutrophils.

central nervous system

After starting a pill, some patients complain about:

  • frequent dizziness;
  • development of depression;
  • loss of consciousness;
  • the appearance of seizures;
  • ataxia and neuropathy.
From the drug may occur side effects like loss of appetite.
From the drug may occur side effects like abdominal pain.
From the drug may occur side effects like an itch of the anus.
From the drug may occur side effects like loss of consciousness.
From the drug may occur side effects like cramps.

On the part of the urinary system

In rare cases appear:

  • crystalluria;
  • interstitial nephritis.

Severe side effects require discontinuation of the drug.


Increased patient sensitivity to the composition of the tablets or the reaction to this group of antibiotics leads to the appearance of:

  • rash;
  • itching;
  • Stevens-Johnson syndrome;
  • urticaria;
  • erythema multiforme;
  • dermatitis (exfoliative or bullous);
  • pustular disease of exantmatous acute.
There may be a side effect from taking the drug like itching.
There may be a side effect from taking the drug like urticaria.
From taking the drug may occur side effects like dermatitis.
From taking the drug may occur side effects like erythema multiforme.
From taking the drug may occur side effects like Stevens-Johnson syndrome.

special instructions

Before taking the drug is recommended to test for hypersensitivity and the appearance of the body's response to cephalosporins and penicillins. Cross-resistance and hypersensitivity may occur between the drugs of these groups.

The most severe hypersensitivity reactions (up to lethal) are observed in those patients who received penicillin therapy. For this reason, special attention should be paid to patients with a history of allergic reactions. In such cases, the drug is replaced by a drug from another group of antibacterial agents.

In the presence of severe disorders of the digestive system, the drug is not recommended to be prescribed in the form of tablets. Vomiting and diarrhea prevent the absorption of the active substance, therefore, the proper effect can not be achieved. For these patients, injections are prescribed.

With long-term treatment with Amoxyl, doctors should regularly monitor the patient’s condition. This is due to increased growth in the number of fungi or bacteria that are not sensitive to the drug.

Against the background of such changes, superinfection develops. It is important to follow the recommendations of the doctor, hygiene and proper nutrition.

To avoid the appearance of erythematous rash, this drug should not be used to treat patients with infectious mononucleosis and acute lymphocytic leukemia.

A long course of treatment with amoxicillin can cause crystalluria. To avoid this, the patient needs to consume a large amount of fluid.

A long course of treatment with amoxicillin can cause crystalluria. To avoid this, the patient needs to consume a large amount of fluid.

Compatibility with alcohol

The drugs of this drug group are not recommended to be combined with alcoholic beverages. This is due to an increased risk of side effects or overdose symptoms.

Influence on ability to operate mechanisms

During treatment with this drug, patients may experience dizziness, a decrease in the rate of reaction. For this reason, driving for the period of treatment should be abandoned. With increased attention should be controlled mechanisms.

Use during pregnancy and lactation

During the studies, no teratogenic effect was detected. Despite this, doctors rarely prescribe this antibacterial agent to pregnant women. At the same time, the benefits of taking the medicine and the possible risk to the health of the fetus should be evaluated.

During the studies, no teratogenic effect was detected. Despite this, doctors rarely prescribe this antibacterial agent to pregnant women.

During the period of breastfeeding, the active substance penetrates into breast milk in small quantities. Lactation can be continued, however, doctors recommend interrupting the feeding at the time of treatment and transfer the child to artificial nutrition.

Appointment of Amoxil 500 children

Children under 1 year Amoxyl is not prescribed. Children up to 6 years old are recommended another dosage form - tablets with a dosage of 250 mg of the active substance.

Use in old age

In the absence of pathologies of the liver and kidneys, patients in old age do not require correction of the dosage of the drug.


During therapy, it is imperative that the recommended dose and regularity of admission. Otherwise, an overdose may occur. She is accompanied by:

  • vomiting;
  • nausea;
  • diarrhea;
  • violation of water and electrolyte balance.

To stabilize the state, it is necessary to reduce the absorbability of the drug. To do this, wash the stomach, prescribe an osmotic laxative and activated charcoal.

With an overdose of the drug may cause diarrhea.
With an overdose of the drug may cause nausea and vomiting.
With an overdose of the drug may cause a violation of water and electrolyte balance.

Interaction with other drugs

Combined use with Phenylbutazone, Probenecid, acetylsalicylic acid and Indomethacin slows the withdrawal of the antibiotic from the body.

Amoxil weakens the effect of oral contraceptives. At the same time the risk of bleeding increases.

Drugs from the group of drugs with a bacteriostatic effect neutralize the effect of amoxicillin. The list of such drugs macrolides, chloramphenicol, tetracyclines.

The toxicity of methotrexate increases.

When combined with Amoxil, Digoxin is absorbed in larger quantities, therefore its dosage should be adjusted.

Admission with allopurinol often causes skin allergic reactions.


There are several Amoxil analogues on the pharmaceutical market that have a similar composition and effect. Among them:

  • Amoxil powder for injection and tablets with a dosage of 250 mg;
  • Amoxyl K 625 (with clavulanic acid);
  • Amoxicillin;
  • Ecobol;
  • Amosin;
  • Gonoform;
  • Amoxicar;
  • Danemox.

Before taking analogues should consult a doctor.

Quickly about medications. Amoxicillin

Pharmacy vacation terms

Drugs in this group are available only by prescription.

Can I buy without a prescription?

You cannot get pills without a prescription.

Amoxil 500 price

In pharmacies in Moscow, the cost of the drug is 160-200 rubles. per pack (20 tablets).

In pharmacies of Ukraine, the packaging of drugs costs 30-35 UAH.

Drug storage conditions

The medicine should be stored in a place protected from direct sunlight, out of reach of children, at a temperature of + 15 ... + 25 ° C.

Shelf life

At observance of requirements to storage the preparation is valid within 4 years.


The manufacturer is the pharmacological company PJSC "Kievmedpreparat", Ukraine.

Amosin is an analogue of the drug.

Reviews on Amoxil 500

The high efficacy of the drug and a wide range of actions made it popular among doctors. Patients report quick results and few side effects.


Tatiana, ENT doctor, 9 years of medical practice, Moscow.

Sinusitis, otitis, and many other inflammatory diseases caused by bacteria are effectively treated with this drug. The list of advantages of tablets can be called a low price, a relatively rare occurrence of side effects.

Alexander, pediatrician, experience in medical practice for 12 years, Kurgan.

With infectious diseases in children, this drug copes well. The pills can be distinguished benefits: the rapid achievement of the result, the ability to assign children. In this case, be sure to carefully select the dosage.

Of patients

Eugene, 43 years old, Novosibirsk.

The doctor prescribed amoxil for bronchitis. Inexpensive effective drug. The condition improved already on the second day; it was possible to completely relieve the symptoms after 5 days.On the first day there was a slight nausea, the doctor said not to interrupt the course. The result is completely satisfied.

Alena, 32, Moscow.

Urgently had to contact the clinic, as prescribed by a doctor antibiotic did not help from streptococcal infection. Amoxyl was designated as a replacement. It became better in a few days. She took the pills strictly on the recommendation of a doctor. No side effects found.

Watch the video: Can you pass the penicillin allergy quiz? (December 2019).