When it comes to the treatment of type 2 diabetes, Siofor is the most popular remedy.
This medicine has long been considered a recognized medication, necessary to increase the sensitivity of cells to insulin. But this is not the only positive property of this drug.
Thanks to the reception of Siofor, the normal functioning of the cardiovascular system is resumed. Long-term use of this medication leads to weight loss. Siofor has a quality counterpart - Glucophage. The characteristics of these drugs have some differences, but the basis of both drugs is the same active substance.
Which is better: Glucophage or Siofor? This question is asked by doctors of most diabetics who are faced with the problem of choice. To solve the dilemma, you need to know well all the advantages, disadvantages of the two medicines.
The main active ingredient
We have already noted that both drugs are based on an identical active ingredient. It is metformin.
Thanks to metformin, the following phenomena occur in the human body:
- cell sensitivity to insulin decreases;
- in the intestine decreases glucose absorption;
- cells improve glucose susceptibility.
Metformin, only improving the response of the cells, does not stimulate the production of its own insulin. As a result, positive changes occur in the body of a diabetic. Improves carbohydrate metabolism.
Against this background, the appetite decreases. Now, a diabetic needs less food to satisfy his need for food. This is beneficial for the patient - his weight begins to decline. Blood sugar levels are also declining.
The dosage, duration of action of both drugs is determined by the attending physician. So, the basis of the drug may be an active substance with a prolonged action. The effect of reducing the level of glucose in the blood when it is taken is held for a long time.
Tablets of the prolonged action Glyukofazh Long
In this case, the word “Long” will appear in the name of the drug. As an example: the drug Glucophage Long normalizes protein metabolism, levels the level of bilirubin in the blood. This drug will need to take only once a day.
The choice of the drug in diabetes is the most important issue. The mechanism of action with the same active substance will be similar. But at the same time we are dealing with two different medications - Glucophage and Siofor.
Sometimes the doctor does not name a specific drug, only gives a list of drugs. The diabetic has to choose the necessary remedy from it independently. To do this, you need a good understanding of all the differences between these drugs.
Use of drugs
Siofor is used to prevent and treat type 2 diabetes.
It is prescribed when the diet, physical activity do not bring the desired results. Siofor is used as a single agent or in combination with other medicines.
It interacts well with drugs that lower blood sugar. These are insulin injections or tablets. The use of Siofor is interconnected with food intake. Gradually, his dose can be increased, but all these actions are taken only after the recommendations of specialists.
Siofor is an excellent means for losing weight. Tablets simply reduce appetite, speed up the metabolism. With the help of the drug, you can easily get rid of a few pounds of excess weight.
Glucophage is considered an analogue of Siofor. It is prescribed to patients with type 2 diabetes. Many patients consider this medicine to be more modern, more effective than Siofor. However, Glucophage has some negative properties.
On the prolonged action Glyukofazha we have already spoken above. And this is his main advantage. The release of metformin here occurs within 10 hours, at Siofor - after 30 minutes. But this applies only to those drugs in the title of which the word "Long" is present. In pharmacies there is a Glyukofazh with a normal, short-acting.
Side effects and contraindications
Side effects of Siofor are minimal, these include:
- slight discomfort in the form of rumbling in the stomach;
- bloating (moderate).
A long series of diseases, conditions in which the use of Siofor is not recommended, is highlighted. These include:
- type 1 diabetes (in the presence of obesity the drug is allowed);
- ketoacid coma, coma;
- the content in the blood, urine proteins globulins, albumin;
- liver disease, its inadequate detoxification function;
- insufficient work of the heart, blood vessels;
- low levels of hemoglobin in the blood;
- surgery, trauma;
- pregnancy, lactation;
- respiratory failure;
- age up to 18 years;
- lack of insulin, which is produced by the pancreas (this can be caused by type 2 diabetes);
- use of oral contraceptives, since the combination of drugs increases the risk of unwanted pregnancy;
- individual intolerance to the components of the drug.
It is undesirable to use this medicine for people over 60 years old if they are engaged in hard physical labor.
Side effects when using Glyukofazh also occur. These include:
- increased body temperature;
- weakness, fatigue.
Most often, these side effects develop against the background of an overdose of the drug. On the part of the gastrointestinal tract undesirable effects may occur if the patient does not follow a low-carb diet.
There are also a number of contraindications in which the use of Glucophage is highly undesirable. These include:
- type 1 diabetes;
- pregnancy, lactation;
- recovery period after surgery, injury;
- diseases of the cardiovascular system;
- chronic alcoholism;
- kidney disease;
- idiosyncrasy drug.
Which drug is better?
Glyukofazh or SioforGlyukofazh and Ziofor - analogues, which include the same active ingredient.
The result of treatment in diabetes of the second type depends entirely on the characteristics of the patient.
The list of side effects in Glyukofazh is somewhat longer. It is probably for this reason that many diabetics choose the familiar Siofor.
But the latter has a significant number of contraindications, so patients are forced to take Glucophage.
As for the latter, it is preferable to choose a drug with a name where the word “Long” is present. Often it is prescribed only once a day, because of this it is not so detrimental to the state of the gastrointestinal tract.
Siofor or Metformin
The composition of both drugs includes one active substance. Which one to choose is up to the patient. Once again, Siofor has a long list of contraindications.
In Metformin, the list of contraindications is shorter:
- diseases of the lungs, respiratory tract;
- diseases of the liver, kidneys;
- myocardial infarction;
- disruption of carbohydrate metabolism caused by insulin deficiency;
- age up to 15 years;
- severe infections;
Overview of drugs Siofor and Glyukofazh in the video:
In order not to be mistaken in the choice of a drug for the treatment of diabetes mellitus type 2, it is necessary to carefully examine the contraindications, side effects. The decisive vote should belong to the attending physician. But if the doctor suggests to choose - take it seriously.